Solid dispersions are one of the key technologies for formulating oral solid dosage forms containing APIs with bioavailability challenges. SDS. Patel, F. Podczeck, Investigation of the effect of type and source of Microcrystalline Cellulose on capsule filling, International Journal of Pharmaceutics, 128 (1996) 123-127. FMC BioPolymer 1735 Market Street Philadelphia, PA 19103 (800) 526-3649 . P}MFbN#[>r(y endobj This grade of polymer film remains intact at pH< 6, thus protecting the API in gastric environments. IFF has decades of experience controlling these naturally derived materials, which means you can count on consistent performance, every time. CAS No. <> stream Cellulose microcrystalline Revision Date 25-Dec-2021 SARA 313 Not applicable SARA 311/312 Hazard CategoriesSee section 2 for more information CWA (Clean Water Act) Not applicable Clean Air Act Not applicable OSHA - Occupational Safety and Health Administration Not applicable CERCLA Not applicable California Proposition 65 This product contains the following Proposition 65 chemicals. 2008-2023 ChemPoint. It is highly versatile and is therefore also widely used in topicals and semi-solid & liquid dosage forms, including ointments, creams, gels, pastes, solutions, suspensions, and emulsions. Avicel PH-101. Powder becomes slippery when wet. To overcome the pitfalls of known overlays, we tested suspensions of microcrystalline cellulose Avicel RC/CLtrade mark as overlay media in the plaque and plaque-inhibition assay of influenza viruses. Medium size standard MCC grade, suited for the majority of directly compressible actives. 1 0 obj %PDF-1.5 Millipore. Explore how we work and why we apply science and creativity for a better world to everything we do. /Producer(Sub Systems, Inc.)/CreationDate(D:20211228124915+05'00')/ModDate(D:20211228124915+05'00')/Creator(Sub Systems, Inc.) Microcrystalline cellulose (MCC) is the most commonly used spheronizing aid in a formulation undergoing extrusion spheronization. . AFFINISOL HPMC has been specifically designed for generating solid dispersions via spray-drying (SDD) or hot melt extrusion (HME) in the pharmaceutical industry. Explore how you can develop your career and bring your creative ideas to life at IFF. Are you looking for information about products and services by region? Safety Data Sheet for Cellulose microcrystalline 102331. endobj Non-woody sources are also viable sources of cellulose, although only woody plants and cotton are the main sources for microcrystalline cellulose used as a pharmaceutical excipient. Dyvo5bp#bR W7~IF C" d6zLz~!#>@HO}sx;hm>> <> Avicel Microcrystalline cellulose is manufactured in the United States of America by Dupont. The United States Food and Drug Administration considers microcrystalline cellulose a safe material for all animal species. PDF (4.11 mb) Footer menu 1. on Avicel microcrystalline cellulose, the most trusted excipient brand for decades. No. The chemical structure of cellulose is shown below: In the biosynthesis of cellulose, two molecules of -D-glucose molecules combine via a condensation reaction (elimination of one molecule of water) to form the so-called cellobiose unit. Carboxymethyl Cellulose Sodium N/A Nutrition & Biosciences www.pharma.dupont.com HO 00017 - 0 E L 02.2020 www.dupontnutritionandbiosciences.com . The highly reactive amorphous regions selectively hydrolyze, releasing the crystallites, which are subsequently mechanically dispersed. Wu, K. Zuurman, H.W. Material Safety Data Sheet TALSTAR S INSECTICIDE Version 1 Page 1 / 8 SDS # : 6320-A This MSDS has been prepared to meet U.S. OSHA Hazard Communication Standard 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS) requirements. Description:Chemical PropertiesMicrocrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles. X\o^ . (AEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEM %)piQpFNnFu\4m4( ESE;m& %QL((((((((((((((((((((((((((((((((((((((((P3NhC 4 0 obj It is a white, free-flowing powder. : 9004-34-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Microcrystalline Cellulose / Avicel PH-102. Manufactured by: China . l~5C Enter your [postal] code to see information about local products, representatives and retailers, along with special offers in your area. Accumulation of overhead settled dust may form explosive concentrations in air when disturbed and dispersed. G2W4de=u183KGH{ vQ#4:1\wc Validity Area. It flows and compresses extremely well, properties that endear this material wide scope of use in many fields. 6 It is generally regarded as a relatively nontoxic and non-irritant material that is safe for human and animal consumption. The most. Learn about FMC's industry leading goal of net-zero emissions by 2035. Packaging: 34 x 50 kgs fiber drums. };khd5x=fr Unique functionality for a broad range of pharmaceutical applications. ChemicalBook. >> XiDqLN MD'F2`jI7ZWu,JK%5e9~:R>LAm\WyY0lk=ZNP;pZ23)P0GG~%e[ d8GIXRo&. % Avicel Microcrystalline cellulose is composed of insoluble fibre and does not contribute any other material of nutritional importance. Created Date: 2/10/2020 8:51:41 PM . ( We are the leading manufacturer of Microcrystalline Cellulose coated with - RC 581 Grade in the industry. ETHOCEL premium ethylcellulose resins are water-insoluble polymers. Currently, it is marketed both directly and indirectly (through distributors) depending on the country in question. Molecular weight: Not Applicable 1.5. Page 1 of 8. Avicel Microcrystalline Cellulose Physical Properties. LATTICE Microcrystalline Cellulose has many important uses within the food, pharma, specialty applications and industrial such as non-stick coatings, insulation of wiring, crop protection and paints,coats and inks. Explore our end markets, products, ingredients and essential solutions or get in touch with us about your order. It is also inert and biocompatible. We are artists at heart and creators by nature. Avicel Microcrystalline cellulose was discovered in 1955 by a team at FMC Corporation, led by the legendary Canadian-born chemist, Orlando Aloysius Battista, which he initially named 'mechanically disintegrated D.P cellulose. <> Some substance identifiers may have been claimed confidential, or may . ( Aqueous suspensions of microcrystalline cellulose have . MATERIAL SAFETY DATA SHEET Avicel RC/CL Microcrystalline Cellulose and Sodium Carboxymethylcellulose MSDS Ref. Microcrystalline Cellulose. To help, weve put together a simple guide for selecting Avicel Microcrystalline cellulose grades, with simple explanations of some of the most common grades, plus recommendations that will serve the majority of buyers. F. Lerk, G.K. Bolhuis, A.H. De Boer, Effect of Microcrystalline Cellulose on liquid penetration in and disintegration of directly compressed tablets, Journal of Pharmaceutical Sciences, 68 (1979) 205-211. It does not interfere with other nutrients when added to food products, and is instead, an excellent carrier and stabiliser, helping prolong the viability of food products. Foam Booster/Stabilizer; Rheology Modifier; Stabilizer-Emulsion; Suspending Agent . Product name: Microcrystalline cellulose; CBnumber: CB4217972; CAS: 9004-34-6; EINECS Number: 232-674-9; Synonyms: MICROCRYSTALLINE CELLULOSE,cellulose; Burger King, McDonald's and other fast food companies list in the ingredients of several of their foods, microcrystalline cellulose (MCC . Aquacoat CPD is an aqueous dispersion of cellulose acetate phthalate used for enteric release applications. Material safety data sheet (MSDS) of the m icrocrystalline cellu lose (MCC) Avicel co-processed products are high functionality excipients offering improved powder flow, granule properties, tablet compression, and mouth feel. Microcrystalline cellulose (MCC) is one of the most important tableting excipients thanks to its outstanding dry binding properties, enabling the manufacture of tablets by direct compression (DC). Kristensen, T. Schfer, P. Kleinebudde, Direct pelletization in a rotary processor controlled by torque measurements. Heavy metals, % NMT 0.001 However, consumption of large quantities of the material may have a laxative effect. You have already flagged this document.Thank you, for helping us keep this platform clean.The editors will have a look at it as soon as possible. Microcrystalline Cellulose, Colloidal Silicon Dioxide: 50: 0.20 - 0.30: Best in class binder. MATERIAL SAFETY DATA SHEET. Assay for carboxymethycellulose sodium, wt % 8.3 to 13.8 . Place an order online, track your orders, download SDS and TDS, and see your quotes, all in one secure place. Request media, explore upcoming events and read our latest updates. Avicel Microcrystalline Cellulose is a safe and non-hazardous material that is widely used in pharmaceutical formulations and food products (as a bulking agent and to add crispness). It is available in different grades and particle sizes. Trademarks: Avicel PH-102. Microcrystalline Cellulose / Avicel PH-102. X]s ;/4'OslUK:|QY`IL|w @ I!*2T~IN?*}y2*49]yOQ*VG%Gu,;&9zE{q==xvrv}rd(yG*qN6E0K$IBWhe Combinations of microcrystalline cellulose (MCC) and sodium carboxymethyl cellulose (Na-CMC) are commonly used as stabilising agents and suspending agents in pharmaceutical formulations. 51395-75-6 Avicel RC 591. PROSOLV SMCC, silicified microcrystalline cellulose, is a unique combination of microcrystalline cellulose (MCC) and colloidal silicon dioxide (CSD).A high functionality and multifunctional excipient, it requires less complex processing, has high inherent functionality, and passes that functionality on to the drug formulation. Cellulose, microcrystalline | C14H26O11 | CID 14055602 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . By producing Avicel . All rights reserved. < gV2@o2s&WS@Et%Up:`U '_ h?8qyP=&> GFprm9A!uu1 }&*kQ c^&eX}^K}h9YCb2L(yL):,+g8_u. ( Are you sure you want to delete your template? Product and Company Identification Product Name Microcrystalline Cellulose CAS Number 9004-34-6 Parchem - fine & specialty chemicals 415 Huguenot Street New Rochelle, NY 10801 (914) 654-6800 (914) 654-6899 parchem.com info@parchem.com EMERGENCY RESPONSE NUMBER This unique functionality can be used in a diversity of applications such as controlled release dosage forms, enteric coatings, microencapsulation and stabilization in solutions and suspensions. Quick Links. METHOCEL cellulose ethers are water-soluble polymers derived from cellulose. Co-processed excipients deliver functional synergies to address formulation challenges with simplified, single ingredient solutions. J]3yzZ2Z$mZ7o%-Xyq'()V9KX0gk~AA Cu:3(]N"AQdUt~h|P <> }o]X4]. AFFINISOL HPMC HME offers hot melt extrusion process flexibility in choosing a polymer viscosity that optimizes drug release profiles and against the factors affecting solubility. SUBSTANCE IDENTIFICATION 1.1. Microcrystalline cellulose (C6H10O5)n is refined wood pulp. We know that our customers need to provide reliable and consistent products to their patients. Aquacoat sustained release coating is a pseudo latex aqueous dispersion of water insoluble polymers used for sustained and enteric coating applications. An agricultural sciences company. Chemsrc provides Cellulose microcrystalline(CAS#:9004-34-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. To meet their exacting standards, we deliver a wide choice of relevant solutions that are simultaneously replicable, scalable and high performing. CAS #: 9004-34-6 . /MediaBox [0 0 612 792] microcrystalline cellulose and carboxymethylcellulose sodium NF, Ph. . Fiber supplements can lessen the absorption of some . An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical tablets, capsules, and granules. As one of the most robust and efficient excipients, it tolerates high salt content, high temperature and is stable in a wide pH range. endobj stream } !1AQa"q2#BR$3br They are high molecular weight, highly sulfated, linear molecules with a galactose backbone. The main source of cellulose is woody plants, since it is the main building block of the cell walls of higher plants. CeolusTM UF-702, MSDS No.060EU MATERIAL SAFETY DATA SHEET NTP: Not listed ACGIH: Not listed 12. No. INCI. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. endobj Description: Microcrystalline Cellulose E460 is a term for refined wood pulp manufactured through plant fibre hydrolysis. There have always been two different points of view for the liquidity of MCC. With an account you can check out faster, view your online order history and access your shopping bag or saved items from any device. This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication. Microcrystalline cellulose was negative in the Ames mutagenicity assay [FMC Study Number I91-1189], and caused no LOT #: Available upon request. xv}O2' H~KEe9>G/,:9\i SCMm_>x^O9l (n. Material Safety Data Sheet or SDS for Microcrystalline cellulose 9004-34-6 from chemicalbook for download or viewing in the browser. "R}~Q:~pgg'"l/O:OV~ @zo7g;)K;=d'}z8}7w7?Iuw?w~ikK^^'d4k;g_u_LOC6($uiz["Dw#j{ogw~0B"ty'{DqXmImPiww#({LDo^/w;?EW>;b$l/fmQ-1GG/jls}>N\UbZWi,`:O?e;hD8}uC?L{yiD>_2?0 :f =eU}|r=r?P5){{o:tzY- F kNdOaM;p0Nmm7A!Va/eWzgT5vw Ur?0J. Product and Company Identification . The product range encompasses methylcellulose and hydroxypropyl methylcellulose (hypromellose) each available in different grades to address a wide range of applications including tablet coatings, granulation, controlled release, drug layering, vegetarian hard-shell capsules and amorphous drug stabilization. 1.3. Formulators select it when they need to enhance a formulations robustness especially when less compactable diluents and binders are used. Our customers around the world enjoy the benefits of TEXTURECEL NaCMC in various wound care products, too. msdsinfo@fmc.com (Email - General Information) FMC Europe NV Avenue Mounier 83 1200 Brussels, Belgium 353 21 435 4133 (General Information - Cork, 86dXeaAjHe%d*`&>>&_p}=X|_% fTtC aB s!YaxHWtGr"GQ 5S"fMS+_;x@@5 zjrK=;OA:il)b> e ei'wm~oh!=Z@Y:J0#8On`T./iC}^o%7KS"$ rf*Z;JTL-uOHH%%Z,029J_ ( endstream endobj 526 0 obj 465 endobj 527 0 obj << /Filter /FlateDecode /Length 526 0 R >> stream Pharmacel 112 is a directly compressible microcrystalline cellulose grade with a low moisture content (LOD Max. Buy Chemicals. Microcrystalline Cellulose; Cellulose; Functions. Avicel PH-200 microcrystalline cellulose NF, Ph. 0.25 - 0.37. : 9 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication . : 5. 2 0 obj Material Safety Data Sheet or SDS for Cellulose microcrystalline 102331 from Merck for download or viewing in the browser. 5 0 obj cas:9032-51-3 msds CELLULOSE PAB. Product Name: MICROCRYSTALLINE CELLULOSE Date/ Revised: 27/November/2012 Page 1 of 4 1. The fumarate moiety of Alubra increases its melting temperature, which allows for greater functionality at high press speeds while the stearate chain maintains the lubricity of the compound and supports low ejection forces. Within the pharmaceuticals field, where the bulk of this material is utilised, Avicel Microcrystalline cellulose functions as a filler and diluent, dry binder, flow, disintegrating, and compression aid in tablets, capsules, and granules. MATERIAL SAFETY DATA SHEET Version: 1.0 1. Truly distinctive drug delivery solutions. %PDF-1.4 High performance lubricant that brings more to the tablet. Product Name Cellulose microcrystalline. Examination of urine, blood and faecal levels of vitamin B 1 during microcrystalline cellulose ingestion showed no difference from control periods (Anonymous, 1966). This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication /Producer(Sub Systems, Inc.)/CreationDate(D:20181207095625+05'00')/ModDate(D:20181207095625+05'00')/Creator(Sub Systems, Inc.) If breathing is difficult or if . These grades have particle sizes ranging from <30 to approximately 200. EMCOCEL 90 M. 130. This Microcrystalline Cellulose . 10.1 Future Forecast of the Global Microcrystalline Cellulose Market from 2023-2028 Segment by Region 10.2 Global Microcrystalline Cellulose Production and Growth Rate Forecast by Type (2023-2028 . Origin(s): Plant/Botanical. Avicel Microcrystalline cellulose is a type of cellulose, a naturally-occurring, large molecular weight polysaccharide found in woody plants. Earth Supplied Products LLC. Its used in capsules and tablets, both in wet granulation and direct compression processes, where it serves as a moisture adsorbent, tablet, and capsule diluent, and tablet disintegrant.It is also widely used as a supplementary formulation aid, primarily to enhance the . Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. 1 0 obj !(!0*21/*.-4;K@48G9-.BYBGNPTUT3? Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents. 1.3. Delivering efficient and robust formulations. Avicel PC 611 Microcrystalline Cellulose. 1. The MCC can be synthesized by different processes such as reactive extrusion, enzyme mediated, steam explosion, and acid hydrolysis. Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives. It should be noted that native cellulose itself is completely indigestible, and its hydrolysis during the production of microcrystalline cellulose does not alter its behaviour in the intestine. Microcrystalline cellulose is produced by subjecting to a high shear treatment, at elevated temperature and pressure, a reaction mixture of a cellulose material, an active oxygen compound and water, for a time effective to depolymerize the cellulose material. HMo@9, U Q!R/1*;` All Rights Reserved. Have an order or account question, find answers in our Online Support articles. ]c\RbKSTQ C''Q6.6QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ p@" /Parent 3 0 R Instead, they obtained a stable colloidal suspension. Eur., JP Product Specifications: Chemical and Physical: Loss on drying 2.0 - 5.0 %* Bulk density 0.29 - 0.36 g/cc Identification A, B Passes Degree of polymerization NMT 350 units pH 5.5 - 7.0* Conductivity NMT 75 S/cm Microcrystalline cellulose -The oldest polymer finds new industrial uses,. Doses up to 30 g per day appear to be . Find answers in our support articles. Tel: 1-239-598-5088 sales@espllc.us www.espllc.us. It is hygroscopic and insoluble in water. X`I%&/m{JJt`$@iG#)*eVe]f@{{;N'?\fdlJ!?~|? Meet our leadership team. MATERIAL SAFETY DATA SHEET Avicel PH Microcrystalline Cellulose MSDS Ref. Ac-Di-Sol Croscarmellose Sodium is one of our flagship offerings for pharmaceutical manufacturers. The typical mean particle size is 20200 m. pH 6.0 to 8.0 . Cellulose microcrystalline. >> iq/iVO"5VI}dn.#q^(fJ),BN yb5*4reh1"!E?mR*%fK,e4?A\{OAXr1' tx&Ul{J,57n%PV E2eMS5'UOL wdD{s)4N-m ab K * ~CVHg}{J2.M}O)^}|Z{V+ >AW|? eqgP}OF'v7heLP&Y,eoo`x7lR}0iRVP],=`_2rS'*X$b)+XV2;fbQDgkgx:IZ|v>lDD/TDqz %RL Description: Microcrystalline Cellulose is a term for refined wood pulp manufactured through plant fibre hydrolysis. LATTICE Microcrystalline Cellulose by Dupont, is an alpha cellulose obtained from naturally ocurring cellulose found in wood pulp, which is an equal structuring polysacharide that is found on fruits and vegetables. Revision No. gwf;J(e0o|1p{R~P^);ao!%{0KD7. Frijlink, Compaction mechanism and tablet strength of unlubricated and lubricated (silicified) Microcrystalline Cellulose, European journal of Pharmaceutics and Biopharmaceutics, 59 (2005) 133-138. %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz % They are differentiated from each other by the amount of 3,6-anhydrogalactose as well as the number and position of ester sulfate groups present. pb7c8BHqCRX_eL +90w~ gk[YBkf9eDNJdNn q^16mi=4Sr0~{lZ>yvMqS'e,MqB?;Oy9s'$8asJgEh0SS>|J58ub^q c Dh)#t'kTfIZT1-_y"+wXj,qo!~ozc}ZemZ``$'vj{, Ga;]2iY*DIh~F3Z!.pkL:bHHBTbIcw9.Xo$4,?On4s=R,KLz /M|#PF(j%j oF2[5 ,rx)bd1$LM4Dc-d\@W D?A?L/7>s]-};Z if^+e3}AeQ# U%l3K?WW$iJ:tSS8M /&N2R3d2Nl2u]qg*WVkq2lhJZIiE++nKfq)sO~z(d| 7u4w!o}::#l}tEw'M}BEntaugq**t|KZUTe-1J+|. Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses CN103842425B . Date Approved: 05/25/2010. Avicel is a brand name by Dupont for grades of Microcrystalline cellulose. Microcrystalline cellulose is a commonly used excipient in the . Revision No. stream (1962). An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical tablets, capsules, and granules. The cellulose molecule is formed through repeated condensation of cellobiose units. PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME: Avicel PC 611 Microcrystalline Cellulose CHEMICAL FAMILY: Carbohydrate, Cellulose Derivative SYNONYMS: Microcrystalline cellulose (INCI name): MCC, cellulose gel; Sodium Carboxymethylcellulose: NaCMC, CMC, SCMC, Carboxymethylcellulose GENERAL USE: Personal Care MANUFACTURER FMC BioPolymer 1735 Market Street Philadelphia, PA 19103 (800) 526-3649 (General Information) msdsinfo@fmc.com (Email - General Information) FMC Europe NV Avenue Mounier 83 1200 Brussels, Belgium 353 21 435 4133 (General Information - Cork, Ireland) 2. {ddn(Y?I#K-}t|l #:FHF'D)/)"{k\pM @LRvdSbi#$yg+\0-U VE-2CZ*K&V.MiLeu86)23NI+6tkLSfmWuR.T\>;8]$ipHJ_)*P.FHyD R^PQ4EC l 4h+:6:]=3?B}Y#eAs(l)V6IOG,OM4'R3#^Op?gYZ; m#6@6O$ ;Ro|U$NSs*\neT &CcB7ysrg7;6Eax $R9+q,)}YK-0/SI0K}d WQC}>e|Gs_Q'+mB| X{URv/Z'` 4w'8sC~ cON&pIk:F/Q&u~.S{"% pg:lfx -. Microcrystalline cellulose has excellent compressibility properties and is widely used in solid forms such as tablets that are hard, but can dissolve quickly, and this has increased its demand in . Standard, 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS . Microcrystalline Cellulose NF. A family of polysaccharide products that allow distinctive drug delivery solutions. Have an order or account question? CAS #: 9004-34-6 Regulatory Information Various Gelcarin and Viscarin carrageenan grades are used by the pharmaceutical industry to achieve specific gelling for controlled drug release, thickening, and stabilizing properties desired in various formulations. Ui[(lY[|//o)ZmqbQT-Y.M|se[)m?(WRV.W8J/j}9>X.VNsZNOp'^14nuXM%rea5]@ MKnNe Microcrystalline cellulose 9004-34-6 232-674-9 Not Listed * Magnesium stearate 557-04- 209-150-3 Not Listed * MSDS Ref. HAZARDS IDENTIFICATION EMERGENCY TELEPHONE NUMBERS (302) 451-0100 (FMC Plant - Newark, Delaware) (303) 595-9048 (Medical - U.S. - Call Collect) For leak, fire, spill, or accident emergencies, call: (800) 424-9300 (CHEMTREC - U.S.A. & Canada) (703) 527-3887 (CHEMTREC - Collect - All Other Countries) EMERGENCY OVERVIEW: Off-white, free-flowing, odorless powder. FMC has deep roots in the food production system worldwide learn more about our latest advances in the future of agriculture. vdZ@Rgl{eU+7N!3!|hUmW)~}U*7k i@j)q["MEydtP"ftFu]t }JN~A"8lz7#}J.i@ qaj/QU<5OrVMfl{pL? Production of Pharmaceutical Grade Microcrystalline Cellulose. Researcher's newest research report, the "Wood Pulp Based Microcrystalline Cellulose Industry Forecast" looks at past sales and reviews total world Wood Pulp Based Microcrystalline Cellulose sales in 2022, providing a comprehensive analysis by region and market sector of . q9;v80q>jZ However, if handling bulk powders, observance of appropriate safeguards is recommended. However, it yields non-digestible fibre. Quantity: 1 700 kgs. Report Category. /Type/Page . LATTICE Microcrystalline Cellulose by Dupont, is an alpha cellulose obtained from naturally ocurring cellulose found in wood pulp, which is an equal structuring polysacharide that is found on fruits and vegetables. It is an excipient approved for use in pharmaceutical products and is also GRAS listed and accepted for use as a food additive in Europe and the United States and is included in the FDA Inactive Ingredients Database (oral: powders, suspensions, syrups, and tablets; topical & vaginal products). q9;v80 The application areas for Avicel Microcrystalline cellulose are immense and encompass many industrial sectors such as food, pharmaceuticals, and cosmetics. DC remains the most economical technique to produce large batches of tablets, however its efficacy is directly impacted by the raw material attributes. The Microcrystalline Cellulose monograph will be incorporated into and become official with the Second Supplement to . The current product range and recommended usage are summarised below: Microcrystalline Cellulose is currently listed in the United States Pharmacopoeia and National Formulary, the European Pharmacopeia, the Japanese Pharmacopoeia, the British Pharmacopoeia, in addition to the Indian and Chinese Pharmacopeia, to name but a few. Microcrystalline Cellulose Side Effects. Chemical Formula: (C6H10O5)n 1.4. It . No: 9004-34-6-5 Version: Global Date Approved: 10/16/1998 . No. 102331. These co-processed products are designed to solve complex formulation problems, simplify manufacturing processes, and deliver significant cost savings. : 5 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication Standard, 29 CFR 1910.1200 and Canadas Workplace Hazardous Materials Information System (WHMIS) requirements. Synergies to simplify formulation challenges and reduce operational costs. GRINDSTED Xanthan Gum readily dissolves in water under ambient conditions without the need of special high-shear equipment. Home. POLYOX resins are nonionic polyethylene oxide solubility polymers. Similarly, the European Food Safety Agency has also evaluated Microcrystalline cellulose and established that it is not absorbed systemically and excreted unchanged. Avicel RC-591 & CL-611 - Description. The global Microcrystalline Cellulose (Mcc) market size is projected to reach multi million by 2026, in comparison to 2022, at unexpected CAGR during 2022-2026.

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